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A few things you know, and some you don’t, about CBD and THC

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CBD, or cannabidiol, is quickly becoming the second most talked about cannabinoid. Here’s how it compares to the most talked about cannabinoid, THC:

1. THC will get you high, CBD will not

For many patients, the main attraction of CBD is that it does not get you high. In fact, medical researchers from the Netherlands Institute of Mental Health and Addiction have observed that CBD counteracts the psychoactive effects of THC. The more CDB is in your cannabis, the less high you are likely to become.

CBD may also help to counteract the memory loss and anxiety sometimes caused by THC. A 2010 study published in the British Journal of Psychiatry showed that subjects given high CBD strains scored better on memory tests and reported lower levels of anxiety than those given high THC strains.

2. Both THC and CBD can help to manage pain

Both THC and CBD can help patients cope with pain, including chronic pain. Patients who received THC as part of a study published in the Canadian Medical Association Journal, reported lower levels of pain along with an improved ability to sleep as a result of their treatment.

Even better is for patients to find a strain with equal parts THC and CBD. A study from the Journal of Pain and Symptom Management shows that cannabis extracts containing a 1:1 ratio of THC:CBD provide more pain relief than those containing just THC.

Why does this work? Researchers at Brown University Department of Psychology have concluded that cannabinoids reduce pain by selectively blocking the signals in the brain and spinal cord that cause us to feel pain.

3. Both THC and CBD can help to manage nausea

Researchers at the University of Guelph in Ontario found that the cannabinoids in cannabis interact with key receptors in the brain to control nausea and vomiting.

A study published in the New England Journal of Medicine showed that 14 of 20 cancer patients experienced less nausea when taking THC. A study on rats at Wilfrid Laurier University concluded that CBD could be a promising treatment for chemotherapy related nausea.

A third study published in the British Journal of Clinical Pharmacology found that 5 of 7 patients suffering from chemotherapy induced nausea and vomiting, who were administered an extract containing equal parts CBD and THC, showed decrease levels of nausea.

4. Both THC and CBD affect mood: While THC may cause anxiety, CBD may reduce it

According to a study published in the Journal of Psychopharmacology, THC can improve mood through euphoria and relaxation, but it can also cause anxiety and disorientation, which may make depression worse.

Most of the research on CBD shows that it reduces feelings of anxiety and depression. For example, researchers at School of Medicine of Ribeirão Preto have shown that CBD reduces anxiety and stress in public speaking tests conducted among individuals with Generalized Social Anxiety disorder.

5. THC increases appetite, CBD may decrease it

The Journal of Palliative Care published a clinical study showing that THC increases appetite and can help cancer patients maintain weight. CBD, however, may actually help to decrease appetite. A study conducted on mice by researchers at the NIH’s National Institute on Alcohol Abuse and Alcoholism seems to show that obesity can be caused by an imbalance of cannabinoids in the body and CBD may be a promising treatment to correct the problem.

So what if you consume a strain high in both THC and CBD? According to German researchers, you’ll still get the munchies. CBD does not counteract the appetite stimulation of THC, like it does the mental effects.

6. Both THC and CBD can help reduce inflammation

According to a 2009 study published in the Journal, Future Medicinal Chemistry, both THC and CBD have qualities that prevent enzymes, called cytokines, from causing inflammation that can allow a tumors to grow and spread.

This could be good news for people with many types of cancer including prostate, colon, thyroid, lung, esophageal, stomach pancreatic and breast cancer, which may cause inflammation.

7. THC and CBD may slow tumor growth

Source: Facebook via Prayers for Sophie

Studies show that both CBD and THC may be effective in slowing tumor growth for certain types of cancer. Here is a summary of some of the current research:

Brain/Glioblastoma

A study by the California Pacific Medical Center Research Institute concluded that both THC and CBD are effective in slowing the growth of brain tumor cells in laboratory cultures, but the most effective treatment is a combination of both CBD and THC.

Leukemia

Researchers at the University of South Carolina School of Medicine, Department of Pathology, Microbiology, and Immunology, have shown CBD may reduce the lifespan of Leukemia cells and reduce tumors.

Lung Cancer

A study published in the British Journal of Pharmacology shows that THC slows the growth of lung cancer tumors in animals and in lab cultures, while a study conducted at University of Rostock, Schillingallee, shows that CBD slows the spread of lung cancer cells.

Breast Cancer

A California Pacific Medical Center, Research Institute study done on breast cancer, shows that CBD can slow tumor growth and reduce tumor aggressiveness, preventing breast cancer from spreading to other parts of the body.

Prostate Cancer

A study on prostate cancer cells, conducted by researchers at the Vancouver Prostate Centre, shows that extracts high in CBD, relative to THC, may be more effective in slowing the growth of prostate cancer cells. The anti-inflammatory effects of CBD also help to treat prostate cancer related inflammation.

Colorectal Cancer

Researchers at the University of Naples Federico II showed that CBD slows the growth of tumors and reduces the spread of colorectal cancer cells in mice. Their research also shows that CBD may have a preventative effect, keeping colon cancer from forming in the first place.

8. THC and CBD tend to work best together

Most forms of cannabis contain a mix of THC and CBD. Several of the studies we came across showed that this is for the best — THC and CBD work well together.

When shopping for a strain, look at the ratio of THC to CBD. If there is more THC, the strain is a high THC strain and will probably make you high. If there is equal parts or more CBD, the strain is high CBD and will not make you high, but may still cause a state change. Whether trying a new THC or CBD strain, always test how it affects you before driving, doing anything potentially dangerous, or engaging in high stakes social situations.

 

Do you prefer high-CBD or high-THC strains? Comment below.

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Five Ways Cannabis Affects Sleep

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Five Ways Cannabis Affects Sleep

Medical patients often suffer from not sleeping well. We dug into recent studies to see if cannabis improves sleep. Here are five things you should know:

THC boosts melatonin

The psychoactive ingredient in cannabis, THC has been shown to dramatically increase melatonin production, causing a spike up to four thousand times that of baseline levels. Melatonin is a naturally occurring hormone that regulates circadian rhythm and sleep.

Increase slow-wave sleep

According to the Department of Psychiatry at the University of San Diego, THC increases the third and fourth stages of the sleep cycle, also known as ‘slow-wave sleep’ (SWS). Increased SWS has been linked to an increased reduction of beta-amyloid, the harmful neural protein associated with Alzheimer’s Disease, dementia, and other memory loss conditions.

Reduce REM

While cannabis is known for increasing SWS, it also reduces the fifth phase of sleep, commonly known as rapid eye movement (REM). Less REM means having less dreams, but there is yet to be any evidence of negative effects.

Treat sleep apnea

Cannabis’ sleep-inducing properties are an excellent natural remedy for those suffering from sleep apnea. This helps them to fall and stay asleep easier and with less interruption.

Reduce RBD in Parkinson’s Disease

By using a high-CBD cannabis before bed, you can lessen REM Sleep Behavior Disorder (RBD) effects such as tremors, violent movements, and nightmares. High-CBD cannabis has been found to be more effective than Levodopa, a prescription drug commonly prescribed to patients with Parkinson’s and onset-RBD.

More Information

Melatonin and marijuana (Lissoni, P., Resentini, M., and Fraschini, F. “Effects of Tetrahydrocannabinol on Melatonin Secretion in Man.”)
Cannabinoids for medical use (Journal of American Medical Association)
Effect of drugs on sleep (National Center for Biotechnology Information)
THC effects on sleep & sleep during withdrawal (Europe PMC)
How Cannabis can help RBD in Parkinson’s (Vanwinkles.com)

Has cannabis had an affect on your quality of sleep? Let us know in the comments section below.

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Grow Medicinal Marijuana At Home With A Grow Box

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Grow Medicinal Marijuana At Home With A Grow Box

Growing your own medicinal marijuana is a liberating experience. You control all the variables. You know exactly what is in the bud you are smoking. grow box is a discreet and easy way to grow marijuana indoors at home, freeing yourself from dependence on both doctor and dispensary.

Gain independence with a grow box

A grow box is like a tiny, camouflaged green house. It is a self-contained unit with soil or hydroponic growing medium, lights, filters and pumps. Just add seeds, electricity and voila! You are growing your own medicinal marijuana.

Choose the right marijuana strain for you

There are two important considerations when choosing a strain of medicinal marijuana to grow yourself:

Your Medical Requirements – Are you looking for a powerful sedative effect to help with your insomnia or a functional day-time smoke to relieve pain and lighten anxiety?

Your Growing Space – Choose small, bushy strains like Indica or hybrid seeds instead of a tall, leggy Sativa. For your first grow an auto-flowering marijuana variety is the best choice because they require very little care or expertise.

Grow enough marijuana to meet your needs

Grow boxes are available in all sizes. Several surveys in the UK, Canada and the US suggest that most medicinal marijuana patients use 1-3 grams per day, or about 2 ½ pounds per year.

Even the tiny PC Grow Box, which holds just two small plants, can produce two pounds of dried bud per year. The compact SuperBox allows you to grow 8 plants at once with annual yields of 7 pounds or more.

Grow your medicinal marijuana under lights

Marijuana grows best under lights that mimic natural sunlight. There are three common types of grow lights used in the cultivation of marijuana:

  • Compact Fluorescent Lights (CFLs)
  • High Intensity Discharge Lights (HIDs)
  • Light Emitting Diodes (LEDs)

Most grow boxes use either CFL or full spectrum LED grow lights. HIDs don’t work well in the enclosed space of a grow box because they get too hot.

While you can grow small amounts of marijuana successfully using CFLs, high quality LED grow lights save electricity and produce the highest yields.

Obtain higher yields using hydroponics

A hydroponic system doesn’t use soil. Growing hydroponic marijuana is not as complex as it may sound.

Many grow boxes come with a simple hydroponic system already set-up. You simply add nutrients, which often come with the grow box, and water. You can even choose to grow marijuana with organic nutrients.

Grow marijuana naturally in soil

Some people prefer to grow marijuana as naturally as possible. The Earth Cab grow box series is one style of grow box designed for soil.

Grow a continuous supply of medicinal marijuana

Once you get started you don’t need new seeds for each growing cycle. You can propagate new marijuana plants by taking cuttings, called clones, of your favorite existing plant.

A dual chamber grow box has a special space for making clones. These grow boxes allow you to produce a constant supply of fresh buds.

Find the perfect grow box for your situation

For the many medicinal growers discretion is essential. Look for a specially designed stealth grow box.

You can also choose a fully automated grow box that allows you to leave town for two weeks and come home to healthy plants.

Use this detailed review of the best grow boxes of 2015 to find the perfect set-up for you.

Grow medicinal marijuana at home with a grow box

Are you considering growing at home? Let us know why in the comments below!

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How Edibles Are Made

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How Edibles Are Made

Since there are so many manufacturers throughout the US, cannabis-infused foods are produced in a variety of different ways. Read up on how your favorite edibles are made and learn how to make your own medicinal treats:

They’re usually made with trim

Trim contains the leftover leaf matter from the cannabis flower that growers usually throw away. It’s less potent than bud, but it’s full of trichomes and can be used in large quantities to produce a stronger effect.

Cannabis is decarboxylated

Decarboxylation activates THC and other cannabinoids to result in a more potent product. To achieve this, cannabis needs to be heated either through smoking, vaping, or baking. The flower is typically cooked for a long time over low heat before it’s used to make edibles. Eating raw cannabis won’t have a very strong effect, and it won’t taste good.

Cannabinoids are extracted

Edibles are infused with highly concentrated cannabis extracts. Depending on the extraction method, edibles can contain either tinctures, canna oil, or cannabutter. If you’re wondering how a specific edible was made, ask your budtender or contact the manufacturer.

Canna oil and cannabutter are common

THC is fat soluble, so cannabis is often cooked with oil or butter. When heated, the activated cannabinoids absorb into these ingredients. Check out this recipe for cannabis cooking oil and this one for cannabis-infused butter. Or try making cannabis coconut oil.

Tinctures are used in hard candies

Some edibles don’t go through a baking or cooking process, so tinctures are added instead of flower. Tinctures are liquid cannabis extracts made from a solvent like alcohol, vinegar, or glycerol. Rather than passing through the digestive system like cannabinoids in most edibles, these are absorbed by the body and can result in a quicker effect.

Have you ever made your own edibles? Tell us in the comments below.

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